Pharmaspire


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Pages: 43-45

Date of Publication: 30-Nov--0001

Potential non-biological therapeutic options for coronavirus disease-2019: Recent updates

Author: Sandeep Kaur, Ghanshyam Das Gupta, Vineet Kumar Rai

Category: Pharmaceutics

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Abstract:

Coronavirus disease-2019 (COVID-19) has been spread across the world and reached to the pandemic level. It has proved as a serious threat to the humanity, therefore, understanding of the ongoing situation and the development of stringent strategies to cure the same is of prime concern. As the potential vaccines development is in continuation, various non-biological therapeutic agents which are being investigated against COVID-19 as a current strategy for symptomatic treatment should be uncovered. To date, various drugs that are approved by the USFDA for their therapeutic effects against rheumatoid arthritis, malaria, influenza A and B and AIDS viruses, pancreatitis, chronic hepatitis C, Middle East respiratory syndrome, inflammation, and immunosuppression are deliberately being used to treat COVID-19 infection. These drugs have shown promising results against this deadly virus. In addition to remdesivir and hydroxychloroquine, oral chlorine dioxide, fluvoxamine, methylprednisolone, losartan, dapagliflozin, and many more have been enrolled for clinical trial and currently recruiting the patients for the studies. This report highlights the potential non-biological therapeutic options used for the treatment of COVID-19, which is expected to help formulation and development scientists to come up with the new technologies of these molecules for better effect against this infectious disease.

Keywords: Coronavirus disease-2019, therapeutic options, hydroxychloroquine, remdesivir, non-biological therapeutic agents

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