<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>isfcppharmaspire</PublisherName> <JournalTitle>Pharmaspire</JournalTitle> <PISSN>C</PISSN> <EISSN>o</EISSN> <Volume-Issue>Volume 15, Issue 04, 2023</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>October-December</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>2024</Year> <Month>02</Month> <Day>17</Day> </PubDate> <ArticleType>Pharmacognosy</ArticleType> <ArticleTitle>In silico studies on Urtica dioica as aldose reductase inhibitors</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>221</FirstPage> <LastPage>224</LastPage> <AuthorList> <Author> <FirstName>Megha</FirstName> <LastName>Goswami</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Priya</FirstName> <LastName>Bisht</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Ghanshyam Das</FirstName> <LastName>Gupta</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Sant Kumar</FirstName> <LastName>Verma</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI>10.56933/Pharmaspire.2023.15133</DOI> <Abstract>Urtica dioica L. is a perennial plant which is commonly known as “stinging nettle.” It is widely distributed throughout the temperate and tropical areas around the world. The genus Urtica is derived from word “uro” which means to burn or “urere” which means to sting. Due to the fact that the plant typically either has male or female blooms, the species name is dioica which means “two households”. Apart from various traditional uses, it is reported for the treatment of diabetes. Owing to the antioxidant potential and presence of flavonoids, here in this research, in silico studies has been performed on U. dioica to establish its target affinity against aldose reductase.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Aldose reductase, Diabetic complications, Molecular docking, Urtica dioica</Keywords> <URLs> <Abstract>https://isfcppharmaspire.com/ubijournal-v1copy/journals/abstract.php?article_id=15067&title=In silico studies on Urtica dioica as aldose reductase inhibitors</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>1. Joshi BC, Kalia AN, Makhija M. Pharmacognostical review of Urtica dioica L. Int J Green Pharm 2014;4:201-209. 2. Taheri Y, Quispe C, Herrera-Bravo J, Sharifi-Rad J, Ezzat SM, Merghany RM, et al. 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