<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>isfcppharmaspire</PublisherName> <JournalTitle>Pharmaspire</JournalTitle> <PISSN>C</PISSN> <EISSN>o</EISSN> <Volume-Issue/> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season/> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Pharmaceutics</ArticleType> <ArticleTitle>Development of spectrophotometric method for simultaneous estimation of dexketoprofen and dicyclomine</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>0</FirstPage> <LastPage>0</LastPage> <AuthorList> <Author> <FirstName>Viney</FirstName> <LastName>CHAWLA</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Objectives: The objective of this work was to develop a simple, fast and reliable UV spectrophotometric method for simultaneous estimation of dexketoprofen and dicyclomine in tablet dosage forms. Methodology: Dexketoprofen and dicyclomine solutions were prepared separately in the range of 2 µg/mL to 10 µg/mL. The solutions were scanned over a range of 200-400 nm. Isoabsorptive point for both drugs was determined. The developed method was evaluated for accuracy, precision and linearity. In linearity correlation coefficient was found. Results: A simple, fast and reliable UV spectrophotometric method was developed for quantitative estimation of dexketoprofen and dicyclomine. Precision study showed that the percent RSD was within the range of acceptable limits, and the percent recovery was found to be in the range of 0.3-1.5 (intraday) and 0.23-1.7 (interday). In accuracy study, the percent recovery was found to be 97 (50%), 96 (100%) and 95 (150%). Conclusion: Developed spectrophotometric method in this study was simple, accurate, precise, specific, sensitive, and reproducible and can be directly and easily applied to pharmaceutical dosage forms.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Accuracy,dexketoprofen,dicyclomine,linearity,precision,pharmaceutical analysis,simultaneous estimation</Keywords> <URLs> <Abstract>https://isfcppharmaspire.com/ubijournal-v1copy/journals/abstract.php?article_id=14960&title=Development of spectrophotometric method for simultaneous estimation of dexketoprofen and dicyclomine</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References/> </References> </Journal> </Article> </ArticleSet>