PHARMASPIRE - Volume 10, Issue 3, July - September, 2018
Pages: 98-106
Date of Publication: 14-Jun-2022
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Recent advances in drug delivery systems in antiviral therapy
Author: Ekta Mishra, Amit K Goyal, Goutam Rath
Category: Pharmaceutics
Abstract:
Intracellular parasitic nature, quick adaptation to antiviral drugs, and rapid mutation pose a great challenge to create an effective therapeutic strategy to combat viral infection. Most of the antiviral drugs have low aqueous solubility, low permeability, and other associated physical properties which make them difficult for the antiviral therapy. Novel drug delivery systems due to their unique surface properties and physiochemical properties enable higher drug solubility, better targeting ability, and enhanced drug stability attracted a great deal of interest in the treatment of viral infections. Novel drug carriers such as liposomes, dendrimer, solid dispersion, microparticles, and nanoparticles are employed to improve therapeutic outcomes. The recent advancements made in the field of antiviral therapy have been discussed in this article.
Keywords: Viral infections, antiviral drugs, mechanism, novel drug delivery
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