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PHARMASPIRE - Volume 10, Issue 4, October - December, 2018

Pages: 164-166

Date of Publication: 14-Jun-2022


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Diclofenac-induced hypersensitivity reaction in a patient suffering from rheumatoid arthritis: A case report

Author: Gurpreet Kaur, Kusheshwar Prasad Singh, Ann Merin Saji, Aseem Sethi, Amit Sharma

Category: Pharmaceutics

Abstract:

Hypersensitivity reactions against nonsteroidal anti-inflammatory drugs like diclofenac (DF) can manifest as Type-I-like allergic reactions including systemic anaphylaxis. Angioedema is a transient subcutaneous or submucosal swelling that is non-pitting when pressure is applied. This case report was collected in the outpatient department of the tertiary care hospital in Punjab. This included a female patient who was having a hypersensitivity reaction on administering drug DF. The patient was diagnosed with drug-induced angioedema of the arm and was asked to discontinue the drug. Complete remission was seen after 1 week of discontinuing the medication.

Keywords: Angioedema, hypersensitivity reaction, nonsteroidal anti-inflammatory drugs

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