PHARMASPIRE - Volume 12, Issue 1, January-March, 2020

Pages: 32-36

Date of Publication: 14-Jun-2022

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To develop and evaluate ultraviolet protective skincare topical formulation

Author: Shivam Singla, Kirandeep Kaur, Veerpal Kaur

Category: Pharmaceutics

Abstract:

Objectives: The main objective of this study was to develop a safe UV protective product with maximum free radical scavenging property. To generate a safe and long acting product against UV radiations. Methods: Selenium Nanoparticles were synthesized by using method chemical reduction. Se Nanoparticles are tested for its particle size, PDI and antioxidant activity. Then these Nanoparticles are incorporated into w/o based cream along with titanium oxide and other excipients. The final formulation was evaluated for its physical appearance, viscosity, texture analysis, globule size and distribution, pH, spreadability and SPF determination. Results: Results of evaluation of elemental Se showed nanoparticle size in nanoscale. The final product that is UV protective topical cream showed required physicochemical properties. Conclusion: The outcomes of this work conclude that the Se nanoparticles and titanium oxide combination was very good as the results indicated.

Keywords: Sunscreen, ultraviolet absorbent, topical formulation, skincare

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