PHARMASPIRE - Volume 12, Issue 3, July-September, 2020

Pages: 84-88

Date of Publication: 10-Jun-2022

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Role of herbal drugs in treatment of alopecia

Author: Jasdeep Sandhu, Veerpal Kaur, Kirandeep Kaur

Category: Pharmaceutics

Abstract:

Alopecia is an autoimmune disorder that occurs due to environmental as well as genetic factors. In this condition, individuals lose hair partially or completely from the scalp and body parts. It is not a painful condition but the physiology of skin may get affected and it affects parsons emotionally and mentally. Patients may develop anxiety and stress. A couple of allopathic drugs are used for treatment such as Propecia and rogaine Propecia stops the conversion of testosterone into 5-alphadihydrotestosterone which is the main culprit for baldness in males. These drugs have many side effects but these are widely used and accepted treatment of alopecia. It has led to the development of hair transplant techniques but they are costly and nonaffordable for masses. Hence, to overcome the side effects of allopathic medicines; nowadays, herbal drugs are preferred for treatment of baldness. These remedies are affected with normal or no side effects.

Keywords: Alopecia, autoimmune disorders, herbs, prevention, treatment

References:

1. Kaushik R, Gupta D, Yadav R. Alopecia: Herbal remedies. Int J Pharm Sci Res 2011;2:1631.

2. Dias MF. Hair cosmetics: An overview. Int J Trichol 2015;7:2.

3. Oranje AP, Al-Mutairi N, Shwayder T, editors. Practical Pediatric Dermatology: Controversies in Diagnosis and Treatment. Berlin: Springer; 2016.

4. Jain PK, Das DE. The wonder of herbs to treat-Alopecia. Innov J Med Sci 2016;4:1-6.

5. Mounsey A, Reed SW. Diagnosing and treating hair loss. Am Fam Phys 2009;80:356-62.

6. Price VH. Treatment of hair loss. N Engl J Med 1999;341:964-73.

7. Gan DC, Sinclair RD. Prevalence of male and female pattern hair loss in Maryborough. J Investig Dermatol Symp Proc 2005;10:184-9.

8. Hoffmann R, Van Neste D. Recent findings with computerized methods for scalp hair growth measurements. J Investig Dermatol Symp Proc 2005;10:285-8.

9. Tsuji Y, Denda S, Soma T, Raftery L, Momoi T, Hibino T. A potential suppressor of TGF-β delays catagen progression in hair follicles. J Investig Dermatol Symp Proc 2003;8:65-8.

10. Gupta AK, Mays RR, Versteeg SG, Shear NH, Piguet V, Piraccini BM. Efficacy of off-label topical treatments for the management of androgenetic alopecia: A review. Clin Drug Investig 2019;39:233-9.

11. Olszewska M, Rudnicka L. Effective treatment of female androgenic alopecia with dutasteride. J Drugs Dermatol 2005;4:637.

12. McElwee KJ, Shapiro JS. Promising therapies for treating and/or preventing androgenic alopecia. Skin Therapy Lett 2012;17:1-4.

13. Gupta AK, Adam P, Dlova N, Lynde CW, Hofstader S, Morar N, et al. Therapeutic options for the treatment of tinea capitis caused by Trichophyton species: Griseofulvin versus the new oral antifungal agents, terbinafine, itraconazole, and fluconazole. Pediatr Dermatol 2001;18:433-8.

14. James J, Saladi RN, Fox JL. Traction alopecia in Sikh male patients. J Am Board Fam Med 2007;20:497-8.

15. Eginli A, Dothard E, Bagayoko CW, Huang K, Daniel A, McMichael AJ. A retrospective review of treatment results for patients with central centrifugal cicatrical alopecia. J Drugs Dermatol 2017;16:317.

16. Xu L, Liu KX, Senna MM. A practical approach to the diagnosis and management of hair loss in children and adolescents. Front Med 2017;4:112.

17. Trüeb RM. Chemotherapy-induced alopecia. Semin Cutan Med Surg 2009;28:11-4.

18. Vasant BS, Bhaskarrao DA, Bhanudas SR. Emblica officinalis the wonder of ayurvedic medicine. World J Pharm Sci 2013;3:285-306.

19. Jain PK, Pandey A. The wonder of ayurvedic medicine Nyctanthes arbor-tristis. Int J Herb Med 2016;4:9-17.

20. Luanpitpong S, Nimmannit U, Pongrakhananon V, Chanvorachote P. Emblica (Phyllanthus emblica Linn.) fruit extract promotes proliferation in dermal papilla cells of human hair follicle. Res J Med Plant 2011;5:95-100.

21. Khan SA, Jameel M, Kanwal S, Shahid S. Medicinal importance of Allium species: A current review. Int J Pharm Sci Res 2017;2:29-39.

22. Mirunalini S, Krishnaveni M. Therapeutic potential of Phyllanthus emblica (Amla): The ayurvedic wonder. J Basic Clin Physiol Pharmacol 2010;21:93-105.

23. Gupta A, Malviya R, Singh TP, Sharma PK. Indian medicinal plants used in hair care cosmetics: A short review. Pharmacogn J 2010;2:361-4.

24. Aliotta G, Petriccione M. Ethnobotany and allelopathy of the Persian walnut (Juglans regia L.). In: 5th International Walnut Symposium, No. 705; 2004. p. 297-300.

25. Pamudji JS, Tri S, Lidia IF. Microemulsion formulation of Aloe vera gel and Apium graveolens ethanol extract for optimizing hair growth promotion. Asian J Pharm Clin Res 2015;8:319-23.

26. Jain VC, Shah DP, Sonani NG, Dhakara S, Patel NM. Pharmacognostical and preliminary phytochemical investigation of Lawsonia inermis L. leaf. Romanian J Biol Plant Biol 2010;55:127-33.

27. Purwal L, Gupta SP, Pande SM. Development and evaluation of herbal formulations for hair growth. J Chem 2008;5:34-8.

28. Kumar N, Rungseevijitprapa W, Narkkhong NA, Suttajit M, Chaiyasut C. 5α-reductase inhibition and hair growth promotion of some Thai plants traditionally used for hair treatment. J Ethnopharmacol 2012;139:765-71.

29. Rathi V, Rathi JC, Patel A, Tamizharasi S. Hair growth activity of Cicer arietinum Linn. Ocimum sanctum Linn and Cyperus rotundus Linn in Albino rats. J Pharmacogn Phytochem 2017;6:157-9.

30. ElMardi MO. Factors Contributing to the Initiation of Growth and Differentiation of Jojoba (Simmondsia chinensis (Link) Schneid.) In Vitro, Dissertation. 31. Shuster S, Thody AJ. The control and measurement of sebum secretion. J Investig Dermatol 1974;62:172-90.

32. Bakeer HM, Abu-Naser SS. Photo Copier Maintenance Expert System V. 01 Using SL5 Object Language. Int J Eng Inf Syst 2017;1:116-24.

33. Tsuji N, Moriwaki S, Ohuchi A, Suzuki Y, Inventors; Kao Corp, Assignee. Treating Method for Suppressing Hair Growth. United States Patent US, No. 7,211,278; 2007.

34. Wijaya WH, Mun’im A, Djajadisastra J. Effectiveness test of fenugreek seed (Trigonella foenum-graecum L.) extract hair tonic in hair growth activity. Int J Curr Res 2013;5:3453-60.

35. Gottumukkala VR, Annamalai T, Mukhopadhyay T. Phytochemical investigation and hair growth studies on the rhizomes of Nardostachys jatamansi DC. Pharmacogn Mag 2011;26:146.

36. Adhirajan N, Kumar TR, Shanmugasundaram N, Babu M. In vivo and in vitro evaluation of hair growth potential of Hibiscus rosa-sinensis Linn. J Ethnopharmacol 2003;88:235-9.

37. Jadhav VM, Thorat RM, Kadam VJ, Gholve SB. Kesharaja: Hair vitalizing herbs. Int J PharmTech Res 2009;1:454-67.

38. Jain R, Jain NK, Singh N, Gnanachandran AK, Gokulan PD. Development and evaluation of polyherbal ointment for hair growth activity. Group 1937;5:314.

39. DebMandal M, Mandal S. Coconut (Cocos nucifera L.: Arecaceae): In health promotion and disease prevention. Asian Pac J Trop Med 2011;4:241-7.

40. Chizick S, Delorscio R, Inventors; Chizick, Stephen, Delorscio, Rico, Assignee. Natural Preparation for Treatment of Male Pattern Hair Loss. United States Patent US, No. 5,972,345; 1999.

41. Lee YK, Kim JK, Cho HG. The clinical study using oriental medicine extract on male pattern hair loss. J Exp Biomed Sci 2004;2:317-24.

42. Cox-Georgian D, Ramadoss N, Dona C, Basu C. Therapeutic and medicinal uses of terpenes. In: Medicinal Plants. Cham: Springer; 2019. p. 333-59.