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      <Volume-Issue>Volume 15, Issue 02, 2023</Volume-Issue>
      <Season>April- June</Season>
      <ArticleType>Pharmacy Practice</ArticleType>
      <ArticleTitle>Lumpy skin disease virus: An updated overview</ArticleTitle>
          <FirstName>Alok Kumar</FirstName>
      <Abstract>Lumpy skin disease virus (LSDV) is the virus that causes LSD, which belongs to the genus Capripoxvirus, family Poxviridae. It is a transboundary, non-zoonotic, and vector-borne disease. It is transmitted by infected arthropod species such as Aedes aegypti mosquitoes, Ixodid ticks, Stomoxys calcitrans, and Tabanids haematopota spp. For the 1st time in India, LSD has been reported to cause 7.1% morbidity among cattle. Clinical features are high fever, anorexia, reducing milk production, enlarged lymph nodes, nasal discharge, oval and round skin lesions with a diameter of 1 to 5 cm (sometimes big), tears discharge from the eyes, saliva discharge from the mouth, leg swellings, lameness in dairy cattle, and pregnant cows may miscarry, and cattle cannot come into heat for long months. Borders with India, like China and Bangladesh, are currently suffering. We should pay attention to vector control, vaccination with quarantine measures, and vector control to stop the LSDV spread. This review article talks about the introduction and background, etiology, epidemiology, transmission, clinical features, prevention and control measures, vaccination, and the LSD outbreak in India.</Abstract>
      <Keywords>Capri poxvirus, Diagnosis, Lumpy skin disease spread in India, Transmission, Vaccines</Keywords>
        <Abstract>https://isfcppharmaspire.com/ubijournal-v1copy/journals/abstract.php?article_id=14814&amp;title=Lumpy skin disease virus: An updated overview</Abstract>
        <References>1. Gupta T, Patial V, Bali D, Angaria S, Sharma M, Chahota R. A review: Lumpy skin disease and its emergence in India. Vet Res Commun 2020;44:111-8.&#13;
2. Jamil M, Latif N, Bano R, Ali SA, Qaisar MA, Ullah N, et al. Lumpy skin disease: An insights in Pakistan. Pak J Med Health Sci 2022;16:824-4.&#13;
3. Abdulqa HY, Rahman HS, Dyary HO, Othman HH. Lumpy skin disease. Reprod Immunol Open Access 2016;1:25.&#13;
4. Hamdi J, Munyanduki H, Tadlaoui KO, El Harrak M, Fihri OF. Capri poxvirus infections in ruminants: A review. Microorganisms 2021;9:902.&#13;
5. Namazi F, Tafti AK. Lumpy skin disease, an emerging transboundary viral disease: A review. Vet Med Sci 2021;7:888-96.&#13;
6. Khan A, Du X, Hussain R, Kwon OD. Lumpy skin disease: A threat to the livestock industry-a review. Agrobiological Rec 2022;9:22-36.&#13;
7. Harikishan S. Lumpy Skin Disease: Nearly 1 Lakh Cattle Death, Toll almost Double in Three Weeks. Noida: The Indian Express; 2022.&#13;
8. Joolly B, Scaria V. The Evolution of Skin Disease Virus. India: The Hindu; 2022.&#13;
9. Bajeli-Datt K. Current Outbreak of Lumpy Skin Disease Distinct from 2019, Need Large-Scale Genomic Surveilance. Chennai: The New Indian Express; 2022.&#13;
10. Rao LN. Lumpy Skin Disease: Lakhs of Cattle Suffer, Rajasthan Worst-hit. New Delhi: Hindustan Times; 2022.&#13;
11. Munjal D. Explained What is Lumpy Skin Disease in Cattle? Does it Affect Milk we Consume? India: The Hindu; 2022.&#13;
12. Indore Reports Firsts Death due to Lumpy Skin Disease. India: The Times of India; 2022.&#13;
13. Chendge PD, Terde SH, Girigosavi PL. Lumpy Skin Diseases: Transmission, Clinical Signs, Diagnosis, Prevention, Control measures, Treatment. Available from: https://www.fao.org/3/i7330e/i7330e.pdf [Last assessed on2023 Apr 12].&#13;
14. Saltykov YV, Kolosova AA, Feodorova VA. Update of lumpy skin disease: Emergence in Asian part of Eurasia. Acta Vet 2022;72:287-99.&#13;
15. Das M, Chowdhury MS, Akter S, Mondal AK, Uddin MJ, Rahman MM, et al. An updated review on lumpy skin disease: Perspective of southeast Asian countries. J Adv Biotechnol Exp Ther 2021;4:322-33.&#13;
16. Gautam M, Kattel P, Kaphle K. Review on lumpy skin disease and its emerging threat to livestock in Nepal. Vet Sci Res Rev 2022;8:43-51.&#13;
17. Hamdi J, Boumart Z, Daouam S, El Arkam A, Bamouh Z, Jazouli M, et al. Development and evaluation of an inactivated lumpy skin disease vaccine for cattle. Vet Microbiol 2020;245:108689.&#13;
18. Hakobyan V, Sargsyan K, Kharatyan S, Elbakyan H, Sargsyan V, Markosyan T, et al. The serological response in cattle following administration of a heterologous sheep pox virus strain vaccine for protection from lumpy skin disease; current situation in Armenia. Vet Sci 2023;10:102.&#13;
19. Wolff J, Moritz T, Schlottau K, Hoffmann D, Beer M, Hoffmann B. Development of a safe and highly efficient inactivated vaccine candidate against lumpy skin disease virus. Vaccines 2020;9:4.</References>