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PHARMASPIRE - Volume 11, Issue 3, July - September, 2019

Pages: 83-87

Date of Publication: 14-Jun-2022

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Development and characterization of clobetasol propionate loaded nanoemulgel for management of psoriasis

Author: Ankita Dadwal, Raj Kumar Narang

Category: Pharmaceutics


The aim of the present study is to formulate clobetasol propionate loaded nanoemulgel for the treatment of plaque psoriasis. Homogenization method is used for the formulation of nanoemulgel and prepared formulation was characterized on the basis of size, entrapment efficiency, polydispersity index, viscosity, spreadability, zeta potential, % in vitro release, in vitro skin permeation, and retention studies. The optimized formulation of nanoemulgel (F2) has shown the significant sustained release of clobetasol propionate.

Keywords: Nanoemulgel, nanoemulsion, permeation, retention, sebaceous gland


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