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PHARMASPIRE - Volume 12, Issue 2, April - June, 2020

Pages: 37-43

Date of Publication: 14-Jun-2022

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Smart nanocarriers: A novel tool for the treatment of ulcerative colitis

Author: Amandeep Singh, Gurmeet Singh, Uttam Kumar Mandal, Raj Kumar Narang

Category: Pharmaceutics


Colitis nanotherapeutics are quickly succeeding and are utilized to sort out numerous restrictions of conventional drug delivery systems such as drug targeting and non-specific distribution with reduced oral bioavailability. Advancement in medical science has put into novel strategies for targeting approaches that may converse new anticipate for ulcerative colitis patients. Numerous beneficial nanocarriers have been commending for clinical use. Nanocarriers have been intended for finest size and surface characteristics to improve their targeting for desired site. Using the pathophysiology of colitis, as an identification marker, their improved permeability and retention effect nanotherapeutics are able to hold loaded active drug to colitis site. In addition, side effects of drugs can also be conquer or reduced using nanocarriers. These nanocarriers are now being vigorously investigated and are on the perspective as the latest generation.

Keywords: Ulcerative colitis, novel drug delivery system, smart carrier, drug targeting, sustain release


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