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PHARMASPIRE - Volume 12, Issue 4, October- December, 2020

Pages: 152-153

Date of Publication: 10-Jun-2022

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Clinical drug-drug interactions of cardiovascular drugs and their case report

Author: Simranjeet Kaur, Kanwalpreet Kaur, Amandeep Singh, Mohit Sharma

Category: Pharmaceutics


This article deals with multifarious range of drug-drug interactions of all types of cardiovascular drugs (e.g., anti-anginal drugs, antihypertensive drugs, etc.) and their severity therein. This piece of work has been formulated after extensive research among various pharmacy-related literatures and contains inputs from all those works therein. DDI in patients receiving multidrug therapy is a major concern. The aim of the present study was to assess the incidence and risk factors of DDIs in patients admitted in the cardiology unit of a teaching hospital. Heparin and aspirin were the most common drugs responsible for DDIs. Bleeding was the most common clinical consequence found in the population. On assessment of severity of DDIs, the majority of the cases were classified as moderate in severity. Aging, female gender, and increase in concurrent medications were found to be associated with increased DDIs. Patients having these risk factors can be actively monitored during their stay in the cardiology department to identify DDIs.

Keywords: Cardiovascular drugs, drug-drug interactions, adverse drug reactions


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