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[An Official Publication of ISF College of Pharmacy, Moga]


 

Original Article
Year : 2019   |  Volume : 11  |  Issue : 4  |  Page : 128-130

Some chalcone derivatives as antimicrobial agents: Synthesis and characterization

Substituted chalcones were synthesized by condensing benzaldehyde derivatives with acetophenone derivatives in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen–Schmidt condensation. In the presence of NaOH/EtOH as a catalyst, various substituted chalcones are synthesized. The reaction is clean with excellent yield. The structures of the synthesized compounds were confirmed by IR and mass spectroscopy.
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