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[An Official Publication of ISF College of Pharmacy, Moga]


 

Original Article
Year : 2019   |  Volume : 11  |  Issue : 4  |  Page : 124-127

Synthesis and in vitro evaluation of silica-based formulations

Background: The cytotoxicity of the silica-based nanoformulations was investigated using non small cell human lung cancer cell line and RAW 264.7 macrophages cell line. Method: The formulations were exposed for 24 h at different dosage levels. 3-[4, 5-dimethylthiazol2-yl]-2, 5-diphenyl tetrazolium bromide assay was used to assess the cell response to the each formulation. Results: The formulations were found to have non-toxic in nature. Conclusion: These nanoformulations could be potentially used for delivering therapeutics for improved biopharmaceutical attributes.
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